NEW APPROACHES IN DIAGNOSIS AND MANAGEMENT OF ACUTE MYELOID LEUKEMIA

This article gives an overview of the literature on the introduction of new approaches in the diagnosis and treatment of acute myeloid leukemia (AML). The methods of cytogenetic and mutation analysis are reviewed, the combinations of using different classes of targeted therapies and immunochemotherapy are described. The results of treatment of patients with AML in different research groups with the assessment of the achievement of complete remission rates, RFS and OS in various prognostic groups are given.