RELATIONSHIP BETWEEN RADIOLOGICAL AND BIOCHEMICAL FEATURES IN CASES OF NUTRITIONAL RICKETS IN INDIAN CHILDREN

Introduction: Rickets is one of the commonest metabolic disorder of growingchildren. In more than 90%,etiology is Nutritional. Disease prevalence is about 50%-90% in developing country like India (16) . Commonest complaint that brings the child to orthopedic OPD isthe deformity of lower limbs and wrist swelling. In this study we have analysed the various radiological and biochemical parameters and found out the relationship between these parameters. Materials and methods: Thirty children with age less than ten years, who were showing signs of nutritional rickets were investigated radiologically andbiochemically. The diagnosed cases of nutritional rickets were followed up overa period of six months. The investigations were repeated at 3weeks, 6weeks, 3months and 6 months. Results: Using students‘t' test and chi square test,Serum alkaline phosphatase wasfound to be most important biochemical variables that statistically correlated with active and healing rickets while cupping was found the most reliable sign of active disease. Conclusion: Radiological and Biochemical investigations correlate well with radiological parameters in case of nutritional rickets. Serum alkaline phosphatase is most useful in diagnosis and treatment of the disease.