PROSPECTS OF CURCUMIN USE IN NANOBIOTECHNOLOGY
Journal: Biotechnologia Acta (Vol.9, No. 3)Publication Date: 2016-06-30
Authors : M. I. Kaniuk;
Page : 23-36
Keywords : curcumin; multicomponent nanocomplexes.;
Abstract
The aim of the work was a generalization of literature data on the prospects for curcumin usage in biotechnology as a component for biologically active nanocomplexes with anti-inflammatory and antioxidant activity creation. It is emphasized that their effectiveness depends on the solubility in aqueous medium and on the metabolism rate decreasing in the body. Current trend is the development of creation methods of hydrophilic curcumin-based nanostructures to increase the time of its biological action. Its nanostructures with silicium, polylysine, copolymers of lactic and glycolic acids and metal ions are the most promising in this respect. For multicomponent hybrid nanoparticles effective usage the substantiation of their component combined use features is necessary. The practical task is to create and to study the functional properties of such combined nanocomplexes. Curcumin complex with metal ions creation contributes to its water solubility and to increase the efficiency of biological action. These complexes have specific characteristics depending on the nature of metal ion. The creation of curcumin-based biocompatible nanocomposites with amplifiers of its action that are known pharmaceuticals is perspective. Such multifunctional nanocomplexes will facilitate the targeted medicines delivery to the places of pathological processes localization and the reduction of their side effects.
Other Latest Articles
- EVALUATION OF EFFECT OF DISEASES ON BETELVINE YIELD
- RELATIONSHIP BETWEEN RADIOLOGICAL AND BIOCHEMICAL FEATURES IN CASES OF NUTRITIONAL RICKETS IN INDIAN CHILDREN
- THE UTILITY OF NOTE-MAKING ?A STUDY
- LEGAL LITERACY GROWING NEED OF THE SOCIETY
- A TO Z SOCIAL MEDIA MARKETING CONCEPTS THAT DRIVES BUSINESS GROWTH
Last modified: 2016-11-11 18:47:59