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One-pot route to nitriles from aldehyde and hydroxylamine hydrochloride on silica-gel

Journal: Asian Journal of Green Chemistry (Vol.2, No. 4)

Publication Date:

Authors : ; ;

Page : 330-337

Keywords : ;

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A green and facile methodology for the synthesis of nitrile has been established from the corresponding aldehydes and hydroxylamine hydrochloride on silica-gel in hot condition. The protocol is equally effective for aliphatic as well as aromatic aldehydes, and has wide range of functional group tolerance. In addition, this methodology is solvent-free, inexpensive, environmental friendly and involves simple work-up process.

Last modified: 2018-07-17 04:16:59