Histological Pattern of Thyroid Malignancies in Tertiary Hospital

Introduction Thyroid cancers are the most common among endocrine malignancies with geographical variation in incidence and histopathological pattern related to age, sex, dietary and environmental factors. The majority of thyroid tumors comprise well differentiated (papillary and follicular) thyroid carcinoma (85 %) and Medullary carcinoma of thyroid represents (5 %). A minority of cases progress to poorly differentiated carcinoma (PDTC) and ultimately to the highly aggressive undifferentiated carcinoma (UTC) or anaplastic carcinoma. PDTC constitutes 1 % to 15 % of all thyroid malignancies. ATC represents 12 % of thyroid cancers. Aim To describe histopathological pattern of thyroid malignancies at a tertiary hospital over a period of 6-years Methods Retrospective study of all thyroid malignancy cases diagnosed among the thyroidectomy patients at endocrine surgery department of a tertiary medical centre in South India from august 2011 to July 2017 The data collected included demographics, clinical presentation, histopathology, treatment, and outcomes Results 386 Thyroid carcinomas were diagnosed over a period of 6 years. Out of 386 thyroid malignancies 354 were differentiated thyroid carcinomas (92 %) and 7 cases of medullary thyroid carcinoma (2 %), 25 cases of poorly differentiated and anaplastic carcinoma were diagnosed which comprises of about (6 %).