H Pylori Associated Chronic Gastritis and Carcinogenic Effect

Helicobacter pylori is one of the most common infection worldwide. H. pylori is a Gram-negative spiral-shaped organism with a flagella, it has been identified as an etiologic factor in the development of peptic ulcer disease because it may colonise in the human gastrointestinal system. Gastric neoplasms such as gastric adenocarcinomas and gastric mucosa-associated lymphoid tissue lymphomas have been linked to H pylori infection. Sensitive and precise diagnostic methods are required for effective antimicrobial treatment. This study summarizes current knowledge about the etiology of chronic gastritis, gastric intestinal metaplasia, and gastric cancer caused by Helicobacter pylori.