ROOM TEMPERATURE SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME 2,5-DISUBSTITUTED-1,3,4-OXADIAZOLES

One of the principles of green chemistry emphasises on minimisation of environmental and economic impacts by developing synthetic reactions at ambient temperature and pressure.The rise of resistant strains of microorganisms is an issue of regularly expanding seriousness. Therefore, the development of new antimicrobial agents will remain a challenge for chemists. we herein report room temperature synthesis of newer heterocyclic compounds belonging to 1,3,4-oxadiazole scaffold. Their structures were confirmed using various spectroscopic techniques. These compounds were evaluated for antifungal, antibacterial and antitubercular activities.