CLINICAL CASE OF ACUTE LEUKEMIA IN A CHILD WITH THALASSEMIA
Journal: Pediatric Bulletin of the South Ural (Vol.1, No. 2)Publication Date: 2020-12-21
Authors : Botalova I.V. Nikonova O.E. Ryskal O.V.;
Page : 82-86
Keywords : thalassemia; acute lymphoblastic leukemia; children;
Abstract
Introduction. The authors describe thalassemia as a group of genetically determined blood diseases and its possible combination with other diseases. The authors cite data from literary sources found by them on the topic under discussion. Clinical case. A 3-year-old patient was diagnosed with congenital hemolytic anemia, a minor form of β-tassemia, and at 6 years of age the child was hospitalized with acute lymphoblastic leukemia. The course of acute leukemia did not require additional blood transfusion load in comparison with other patients. Complete clinical and hematological remission was obtained. Conclusion. The article presents a rare case of the development of acute leukemia in a child who was previously diagnosed with thalassemia. A mild form of hemolytic anemia makes it possible to successfully cope with the manifestations of cytopenic syndrome as a result of the ongoing antitumor therapy. The question of the nature of the relationship between the development of leukemia in a child and thalassemia is discussed in the literature from various positions.
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