SIGNIFICANCE OF HEPATIC MICROCIRCULATION DAMAGE IN DEVELOPMENT OF PATHOLOGICAL CHANGES OF THE LIVER IN EXPERIMENTAL ACUTE PANCREATITIS IN RATS

The visible reaction of hepatic mircocirculation in the experimental models of acute pancreatitis was depended on character of pathomorphological changes in pancreas. This reaction demonstrated the phase character including: 1) activation of hepatic circulation, first of all in portal component; 2) development of inflammatory, dystrophic, destructive and necrotic changes in hepatic parenchyme together with mircocirculation disorders; 3) recovery and adaptation or decompensation processes in mircocirculation system of liver and hepatic parenchyme depending on the degree of pancreatogenic toxemia.