Biogenic Synthesis of Silver Nanoparticles Using Leaves Extract of Epiphyllum Oxypetalum and its Antibacterial Activity

Silver nanoparticles have a huge share in nanotechnology, which offers numerous benefits, including ecofriendliness and compatibility for biomedical applications. Here, we report the synthesis of silver nanoparticles due to the reduction of silver nitrate by an aqueous leaf extract of Epiphyllum oxypetalum. The synthesized silver nanoparticles were characterized by UV-Visible spectroscopy, NTA analysis, FT-IR analysis and Zeta potential. The results showed that silver nanoparticles thus synthesized have an average particle size of 86 nm. The antibacterial activity of the synthesized silver nanoparticles alone and in combination with commercial antibiotics was tested against Propionibacterium acne, Pseudomonas aeruginosa and Klebsiella pneumoniae. From this study, it can be concluded that efficiency of silver nanoparticles increased when accessed in combination with antibiotics against test organisms. Due to pronounced antibacterial activity, silver nanoparticles synthesized by leaf extract of E. oxypetalum can act as effective antibacterial agent for various biomedical applications.