Pengaruh Pemberian Ekstrak Etanol 70% Daun Binahong (Anredera scandens (L.) Moq.) terhadap Makroskopik dan Biokimia Ginjal Mencit Jantan Galur Balb/C

Anredera scandens (L.) Moq. or binahong is a plant whose leaf part has been scientifically proven to have activity as an antiulcer. The purpose of this research is to know and describe the effect of ethanol extract 70% leaf A. scandens (L.) Moq. on macroscopic renal seen from the parameters of renal weight and volume, and renal kidney biochemistry seen from the parameters of BUN content and blood creatinine. Powder and extract first measured its water content. Test effect of ethanol extract 70% leaf A. scandens (L.) Moq. in the kidney was performed on male Balb / C mice once daily for 30 days. Measurements of renal weight and volume, BUN and creatinine levels were performed at the end of the study. Parametric data was analyzed by ANOVA-one way, and nonparametric data was analyzed by Kruskall-Wallis and Mann-Whitney test. The measurement of powdered and extract water content showed results that meet the standard of Herbal Pharmacopoeia Indonesia. Provision of ethanol extract 70% leaf A. scandens (L.) Moq. for 30 days, did not statistically give significant effect to renal macroscopic seen from renal weight and volume parameter and renal biochemistry seen from BUN and creatinine levels.